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NDB ID: PR0094    PDB ID: 1OOA 


Title:

CRYSTAL STRUCTURE OF NF-KB(P50)2 COMPLEXED TO A HIGH-AFFINITY RNA APTAMER

Molecular Description:

Nuclear factor NF-kappa-B p105 subunit/RNA Complex

Structural Keywords:

SINGLE STRAND, LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Huang, D.B., Vu, D., Cassiday, L.A., Zimmerman, J.M., Maher III, L.J., Ghosh, G.
Crystal structure of NF-kappaB (p50)2 complexed to a high-affinity RNA aptamer. 
Proc.Natl.Acad.Sci.USA, 100, pp. 9268 - 9273, 2003.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 76.753   b = 151.059   c = 95.628 (Ångstroms)

α = 90.0   β = 105.95   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.1 program. The R value is 0.208 for 33180 reflections in the resolution range 28.99 to 2.45 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  0.0 sigma(I)