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NDB ID: PR0118    PDB ID: 1SJF     NAKB: PR0118 


Title:

CRYSTAL STRUCTURE OF THE HEPATITIS DELTA VIRUS GEMONIC RIBOZYME PRECURSOR, WITH C75U MUTAION, IN COBALT HEXAMMINE SOLUTION

Molecular Description:

Deposited:

2004-03-03

Released:

2004-05-18

Structural Keywords:

, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Ke, A., Zhou, K., Ding, F., Cate, J.H., Doudna, J.A.
A conformational switch controls hepatitis delta virus ribozyme catalysis. 
Nature, 429, pp. 201 - 205, 2004.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

H 3 2

Cell Constants:

a = 108.754   b = 108.754   c = 188.381 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.24 for 10826 reflections in the resolution range 42.12 to 2.75 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)