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NDB ID: PR0151    PDB ID: 1YVP 


Title:

RO AUTOANTIGEN COMPLEXED WITH RNAS

Molecular Description:

60-kDa SS-A/Ro ribonucleoprotein/RNA complex

Structural Keywords:

A DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Stein, A.J., Fuchs, G., Fu, C., Wolin, S.L., Reinisch, K.M.
Structural Insights into RNA Quality Control: The Ro Autoantigen Binds Misfolded RNAs via Its Central Cavity 
Cell(Cambridge,Mass.), 121, pp. 529 - 539, 2005.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 60.3   b = 153.65   c = 80.56 (Ångstroms)

α = 90.0   β = 92.8   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.1 program. The R value is 0.2021 for 70300 reflections in the resolution range 20.0 to 2.2 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)