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NDB ID: PR0152    PDB ID: 1YTY 


Title:

STRUCTURAL BASIS FOR RECOGNITION OF UUUOH 3'-TERMINII OF NASCENT RNA POL III TRANSCRIPTS BY LA AUTOANTIGEN

Molecular Description:

Lupus La protein/RNA Complex

Structural Keywords:

RH DOUBLE HELIX, FLIPPED-OUT BASES, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Teplova, M., Yuan, Y.R., Phan, A.T., Malinina, L., Ilin, S., Teplov, A., Patel, D.J.
Structural Basis for Recognition and Sequestration of UUU(OH) 3' Temini of Nascent RNA Polymerase III Transcripts by La, a Rheumatic Disease Autoantigen. 
Mol.Cell, 21, pp. 75 - 85, 2006.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 2

Cell Constants:

a = 153.69   b = 54.001   c = 56.684 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC 5.2.0005 program. The R value is 0.22213 for 20734 reflections in the resolution range 40.0 to 2.29 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  0.0 sigma(I)