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NDB ID: PR0170    PDB ID: 1ZZN 


Title:

CRYSTAL STRUCTURE OF A GROUP I INTRON/TWO EXON COMPLEX THAT INCLUDES ALL CATALYTIC METAL ION LIGANDS.

Molecular Description:

U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/RNA Complex

Structural Keywords:

SINGLE STRAND, LOOPS, HAIRPIN LOOP, INTERNAL LOOP, RNA HAMMERHEAD RIBOZYME

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Stahley, M.R., Strobel, S.A.
Structural evidence for a two-metal-ion mechanism of group I intron splicing. 
Science, 309, pp. 1587 - 1590, 2005.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 41 2 2

Cell Constants:

a = 108.466   b = 108.466   c = 246.4 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.0 program. The R value is 0.269 for 18224 reflections in the resolution range 33.04 to 3.37 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)