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NDB ID: PR0173    PDB ID: 2ANR 


Title:

CRYSTAL STRUCTURE (II) OF NOVA-1 KH1/KH2 DOMAIN TANDEM WITH 25NT RNA HAIRPIN

Molecular Description:

neuro-oncological ventral antigen 1/RNA Complex

Structural Keywords:

SINGLE STRAND, LOOP, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Teplova, M., Malinina, L., Darnell, J.C., Song, J., Lu, M., Abagyan, R., Musunuru, K., Teplov, A., Burley, S.K., Darnell, R.B., Patel, D.J.
Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1. 
Structure, 19, pp. 930 - 944, 2011.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 159.453   b = 37.885   c = 38.523 (Ångstroms)

α = 90.0   β = 96.64   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC 5.1.13 program. The R value is 0.23 for 16202 reflections in the resolution range 20.0 to 1.94 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)