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NDB ID: PR0176    PDB ID: 2AZX 


Title:

CHARGED AND UNCHARGED TRNAS ADOPT DISTINCT CONFORMATIONS WHEN COMPLEXED WITH HUMAN TRYPTOPHANYL-TRNA SYNTHETASE

Molecular Description:

Tryptophanyl-tRNA synthetase (E.C. 6.1.1.2)/RNA Complex

Structural Keywords:

T SINGLE STRAND, LOOP, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Yang, X.L., Otero, F.J., Ewalt, K.L., Liu, J., Swairjo, M.A., Kohrer, C., RajBhandary, U.L., Skene, R.J., McRee, D.E., Schimmel, P.
Two conformations of a crystalline human tRNA synthetase-tRNA complex: implications for protein synthesis. 
Embo J., 25, pp. 2919 - 2929, 2006.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

I 21 21 21

Cell Constants:

a = 114.058   b = 132.621   c = 246.633 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.1 program. The R value is 0.211 for 79186 reflections in the resolution range 50.0 to 2.8 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)