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NDB ID: PR0232    PDB ID: 2I91 


Title:

60KDA RO AUTOANTIGEN IN COMPLEX WITH A FRAGMENT OF MISFOLDED RNA

Molecular Description:

60 kDa SS-A/Ro ribonucleoprotein/RNA

Structural Keywords:

A DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Fuchs, G., Stein, A.J., Fu, C., Reinisch, K.M., Wolin, S.L.
Structural and biochemical basis for misfolded RNA recognition by the Ro autoantigen. 
Nat.Struct.Mol.Biol., 13, pp. 1002 - 1009, 2006.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 72.68   b = 119.98   c = 73.54 (Ångstroms)

α = 90.0   β = 98.91   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.1 program. The R value is 0.245 for 34410 reflections in the resolution range 50.0 to 2.65 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)