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NDB ID: PR0250    PDB ID: 1OB5 


Title:

T. AQUATICUS ELONGATION FACTOR EF-TU COMPLEXED WITH THE ANTIBIOTIC ENACYLOXIN IIA, A GTP ANALOG, AND PHE-TRNA

Molecular Description:

ELONGATION FACTOR TU (E.C.3.6.1.48)

Deposited:

2003-01-24

Released:

2005-10-13

Structural Keywords:

T, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Parmeggiani, A., Krab, I.M., Watanabe, T., Nielsen, R.C., Dahlberg, C., Nyborg, J., Nissen, P.
Enacyloxin Iia Pinpoints a Binding Pocket of Elongation Factor TU for Development of Novel Antibiotics. 
J.Biol.Chem., 281, pp. 2893 - , 2006.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 212.57   b = 122.33   c = 135.68 (Ångstroms)

α = 90.0   β = 121.3   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.2796 for 53684 reflections in the resolution range 29.54 to 3.1 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)