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NDB ID: PR0307    PDB ID: 2RE8 


Title:

GLUTAMINYL-TRNA SYNTHETASE MUTANT C229R WITH BOUND ANALOG 5'-O-[N-(L-GLUTAMYL)-SULFAMOYL]ADENOSINE

Molecular Description:

Glutaminyl-tRNA synthetase (E.C.6.1.1.18)/RNA Complex
O5'-(L-GLUTAMYL-SULFAMOYL)-ADENOSINE

Structural Keywords:

SINGLE STRAND, LOOP, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Bullock, T.L., Rodriguez-Hernandez, A., Corigliano, E.M., Perona, J.J.
A rationally engineered misacylating aminoacyl-tRNA synthetase. 
Proc.Natl.Acad.Sci.Usa, 105, pp. 7428 - 7433, 2008.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 237.142   b = 92.907   c = 115.512 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.0 for 37042 reflections in the resolution range 118.6 to 2.6 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)