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NDB ID: PR0313    PDB ID: 3BSN 


Title:

NORWALK VIRUS POLYMERASE BOUND TO 5-NITROCYTIDINE TRIPHOSPHATE AND PRIMER-TEMPLATE RNA

Molecular Description:

RNA dependent RNA polymerase/RNA Complex

Structural Keywords:

A DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Zamyatkin, D.F., Parra, F., Alonso, J.M., Harki, D.A., Peterson, B.R., Grochulski, P., Ng, K.K.
Structural insights into mechanisms of catalysis and inhibition in norwalk virus polymerase. 
J.Biol.Chem., 283, pp. 7705 - 7712, 2008.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 74.31   b = 93.85   c = 96.03 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC 5.2.0019 program. The R value is 0.20251 for 58754 reflections in the resolution range 19.71 to 1.8 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)