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NDB ID: PR0315    PDB ID: 3BSX 


Title:

CRYSTAL STRUCTURE OF HUMAN PUMILIO 1 IN COMPLEX WITH PUF5 RNA

Molecular Description:

Pumilio homolog 1/RNA Complex

Deposited:

2007-12-26

Released:

2008-04-08

Structural Keywords:

SINGLE STRAND

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Gupta, Y.K., Nair, D.T., Wharton, R.P., Aggarwal, A.K.
Structures of human Pumilio with noncognate RNAs reveal molecular mechanisms for binding promiscuity. 
Structure, 16, pp. 549 - 557, 2008.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 35.835   b = 65.642   c = 313.975 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.21845 for 28112 reflections in the resolution range 40.93 to 2.32 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)