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NDB ID: PR0335    PDB ID: 3CIY 


Title:

MOUSE TOLL-LIKE RECEPTOR 3 ECTODOMAIN COMPLEXED WITH DOUBLE-STRANDED RNA

Molecular Description:

Toll-like receptor 3/RNA Complex

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Liu, L., Botos, I., Wang, Y., Leonard, J.N., Shiloach, J., Segal, D.M., Davies, D.R.
Structural basis of toll-like receptor 3 signaling with double-stranded RNA. 
Science, 320, pp. 379 - 381, 2008.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 117.846   b = 225.877   c = 259.53 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.2 program. The R value is 0.288 for 46429 reflections in the resolution range 47.29 to 3.41 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)