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NDB ID: PR0383    PDB ID: 3HJW 


Title:

STRUCTURE OF A FUNCTIONAL RIBONUCLEOPROTEIN PSEUDOURIDINE SYNTHASE BOUND TO A SUBSTRATE RNA

Molecular Description:

tRNA pseudouridine synthase B
Ribosome biogenesis protein Nop10
50S ribosomal protein L7Ae/RNA complex

Structural Keywords:

SINGLE STRAND, HAIRPIN LOOP, LOOP, INTERNAL LOOP

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 3 protein sequences

Primary Citation:

Liang, B., Zhou, J., Kahen, E., Terns, R.M., Terns, M.P., Li, H.
Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA 
Nat.Struct.Mol.Biol., 16, pp. 740 - 746, 2009.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 2

Cell Constants:

a = 186.013   b = 63.026   c = 85.447 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC 5.2.0005 program. The R value is 0.218 for 42200 reflections in the resolution range 46.52 to 2.35 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)