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NDB ID: RR0016    PDB ID: 1FJG 


Title:

STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH THE ANTIBIOTICS STREPTOMYCIN, SPECTINOMYCIN, AND PAROMOMYCIN

Molecular Description:

INHIBITED 30S RIBOSOMAL SUBUNIT

Structural Keywords:

SINGLE STRAND

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 20 protein sequences

Primary Citation:

Carter, A.P., Clemons Jr., W.M., Brodersen, D.E., Morgan-Warren, R.J., Wimberly, B.T., Ramakrishnan, V.
Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics 
Nature, 407, pp. 340 - 348, 2000.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 41 21 2

Cell Constants:

a = 402.001   b = 402.001   c = 176.489 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.221 for 259882 reflections in the resolution range 95.346 to 3.0 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)