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NDB ID: RR0022    PDB ID: 1HNZ     NAKB(beta): RR0022 

Title:

STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH HYGROMYCIN B

Molecular Description:

INHIBITED 30S RIBOSOMAL SUBUNIT

Deposited:

2000-12-08

Released:

2001-02-21

Structural Keywords:

SINGLE STRAND

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 20 protein sequences

Primary Citation:

Brodersen, D.E., Clemons Jr., W.M., Carter, A.P., Morgan-Warren, R.J., Wimberly, B.T., Ramakrishnan, V.
The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit. 
Cell(Cambridge,Mass.), 103, pp. 1143 - 1154, 2000.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 41 21 2

Cell Constants:

a = 402.063   b = 402.063   c = 175.263 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.218 for 187963 reflections in the resolution range 50.0 to 3.3 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)

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