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NDB ID: RR0054    PDB ID: 1M1K 


Title:

CO-CRYSTAL STRUCTURE OF AZITHROMYCIN BOUND TO THE 50S RIBOSOMAL SUBUNIT OF HALOARCULA MARISMORTUI

Molecular Description:

50S RIBOSOMAL SUBUNIT COMPLEXED WITH AZITHROMYCIN

Structural Keywords:

SINGLE STRAND

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 28 protein sequences

Primary Citation:

Hansen, J.L., Ippolito, J.A., Ban, N., Nissen, P., Moore, P.B., Steitz, T.A.
The structures of four macrolide antibiotics bound to the large ribosomal subunit. 
Mol.Cell, 10, pp. 117 - 128, 2002.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 213.751   b = 301.566   c = 574.436 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.0 program. The R value is 0.214 for 276945 reflections in the resolution range 20.0 to 3.2 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)