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NDB ID: RR0071    PDB ID: 1P9X 


Title:

THE CRYSTAL STRUCTURE OF THE 50S LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH TELITHROMYCIN KETOLIDE ANTIBIOTIC

Molecular Description:

50S Large ribosomal subunit

Structural Keywords:

SINGLE STRAND, LOOPS, BULGES, FLIPPED-OUT BASES, BASE TRIPLET

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Berisio, R., Harms, J., Schluenzen, F., Zarivach, R., Hansen, H.A., Fucini, P., Yonath, A.
Structural insight into the antibiotic action of telithromycin against resistant mutants 
J.Bacteriol., 185, pp. 4276 - 4279, 2003.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

I 2 2 2

Cell Constants:

a = 170.0   b = 414.5   c = 693.0 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.28 for 245223 reflections in the resolution range 15.0 to 3.4 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  0.0 sigma(I)