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NDB ID: RR0084    PDB ID: 1XBP 


Title:

INHIBITION OF PEPTIDE BOND FORMATION BY PLEUROMUTILINS: THE STRUCTURE OF THE 50S RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS IN COMPLEX WITH TIAMULIN

Molecular Description:

50S RIBOSOME

Structural Keywords:

SINGLE STRAND

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 29 protein sequences

Primary Citation:

Schluenzen, F., Pyetan, E., Fucini, P., Yonath, A., Harms, J.M.
Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin. 
Mol.Microbiol., 54, pp. 1287 - 1294, 2004.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

I 2 2 2

Cell Constants:

a = 168.7   b = 405.0   c = 693.0 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.0 program. The R value is 0.29 for 258817 reflections in the resolution range 15.0 to 3.5 Ångstroms with Fobs >  1.0 sigma(Fobs) and with I >  0.0 sigma(I)