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NDB ID: RR0116    PDB ID: 1YJ9 


Title:

CRYSTAL STRUCTURE OF THE MUTANT 50S RIBOSOMAL SUBUNIT OF HALOARCULA MARISMORTUI CONTAINING A THREE RESIDUE DELETION IN L22

Molecular Description:

50S Ribosomal Subunit

Structural Keywords:

SINGLE STRAND

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 29 protein sequences

Primary Citation:

Tu, D., Blaha, G., Moore, P.B., Steitz, T.A.
Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance. 
Cell(Cambridge,Mass.), 121, pp. 257 - 270, 2005.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 213.076   b = 300.75   c = 575.478 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.184 for 400720 reflections in the resolution range 29.94 to 2.8 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)