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NDB ID: RR0200    PDB ID: 2QEX 


Title:

NEGAMYCIN BINDS TO THE WALL OF THE NASCENT CHAIN EXIT TUNNEL OF THE 50S RIBOSOMAL SUBUNIT

Molecular Description:

50S ribosomal subunit
negamycin

Structural Keywords:

SINGLE STRAND, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 29 protein sequences

Primary Citation:

Schroeder, S.J., Blaha, G., Moore, P.B.
Negamycin binds to the wall of the nascent chain exit tunnel of the 50S ribosomal subunit. 
Antimicrob.Agents Chemother., 51, pp. 4462 - 4465, 2007.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 214.62   b = 304.048   c = 578.647 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.0 program. The R value is 0.0 for 411517 reflections in the resolution range 49.92 to 2.9 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)