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NDB ID: RR0205    PDB ID: 3CCE 


Title:

STRUCTURE OF ANISOMYCIN RESISTANT 50S RIBOSOMAL SUBUNIT: 23S RRNA MUTATION U2535A

Molecular Description:

50S ribosomal subunit

Structural Keywords:

SINGLE STRAND

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 29 protein sequences

Primary Citation:

Blaha, G., Gurel, G., Schroeder, S.J., Moore, P.B., Steitz, T.A.
Mutations outside the anisomycin-binding site can make ribosomes drug-resistant. 
J.Mol.Biol., 379, pp. 505 - 519, 2008.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 212.832   b = 299.896   c = 576.013 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.0 program. The R value is 0.183 for 379835 reflections in the resolution range 49.33 to 2.75 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)