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NDB ID: RR0207    PDB ID: 3CCL     NAKB: RR0207 

Title:

STRUCTURE OF ANISOMYCIN RESISTANT 50S RIBOSOMAL SUBUNIT: 23S RRNA MUTATION U2535C. DENSITY FOR ANISOMYCIN IS VISIBLE BUT NOT INCLUDED IN MODEL.

Molecular Description:

50S ribosomal subunit

Deposited:

2008-02-26

Released:

2008-05-20

Structural Keywords:

SINGLE STRAND

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 29 protein sequences

Primary Citation:

Blaha, G., Gurel, G., Schroeder, S.J., Moore, P.B., Steitz, T.A.
Mutations outside the anisomycin-binding site can make ribosomes drug-resistant. 
J.Mol.Biol., 379, pp. 505 - 519, 2008.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 213.161   b = 300.032   c = 576.127 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.171 for 371553 reflections in the resolution range 49.98 to 2.9 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)

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