A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 20-Jul-2016 number of released structures: 8375
Search for released structures

NDB ID: RR0214    PDB ID: 3CD6 


Title:

CO-CYSTAL OF LARGE RIBOSOMAL SUBUNIT MUTANT G2616A WITH CC-PUROMYCIN

Molecular Description:

50S ribosomal subunit

Structural Keywords:

SINGLE STRAND

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 29 protein sequences

Primary Citation:

Blaha, G., Gurel, G., Schroeder, S.J., Moore, P.B., Steitz, T.A.
Mutations outside the anisomycin-binding site can make ribosomes drug-resistant. 
J.Mol.Biol., 379, pp. 505 - 519, 2008.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 212.805   b = 299.997   c = 576.002 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.0 program. The R value is 0.193 for 430009 reflections in the resolution range 49.95 to 2.75 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)