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NDB ID: RR0239    PDB ID: 3FWO 


Title:

THE LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH METHYMYCIN

Molecular Description:

23S ribosomal RNA/5S ribosomal RNA

Structural Keywords:

SINGLE STRAND, LOOPS, BULGES, FLIPPED-OUT BASES, BASE TRIPLET

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Auerbach, T., Mermershtain, I., Bashan, A., Davidovich, C., Rozenberg, H., Sherman, D.H., Yonath, A.
Structural basis for the antibacterial activity of the 12-membered-ring mono-sugar macrolide methymycin
Biotechnologia, 1, pp. 24 - 35, 2009.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

I 2 2 2

Cell Constants:

a = 172.499   b = 415.691   c = 701.729 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.2 program. The R value is 0.278 for 251032 reflections in the resolution range 30.0 to 3.71 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)