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NDB ID: UD0016    PDB ID: 1K8P 


Title:

STRUCTURE OF THE HUMAN G-QUADRUPLEX REVEALS A NOVEL TOPOLOGY

Molecular Description:

5'-D(*(BRU)P*AP*GP*GP*GP*(BRU)P*TP*AP*GP*GP*GP*T)-3'

Deposited:

2001-10-25

Released:

2002-05-31

Structural Keywords:

QUADRUPLE HELIX, LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Parkinson, G.N., Lee, M.P., Neidle, S.
Crystal structure of parallel quadruplexes from human telomeric DNA. 
Nature, 417, pp. 876 - 880, 2002.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 31 2 1

Cell Constants:

a = 56.607   b = 56.607   c = 40.546 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.193 for 2572 reflections in the resolution range 10.0 to 2.4 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)