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NDB ID: UHJ055    PDB ID: 1FIX 


Title:

THE STRUCTURE OF AN RNA/DNA HYBRID: A SUBSTRATE OF THE RIBONUCLEASE ACTIVITY OF HIV-1 REVERSE TRANSCRIPTASE

Molecular Description:

5'-R(*UP*UP*CP*GP*GP*GP*CP*GP*CP*C)-3'/5'-D(*GP*GP*CP*GP*CP*CP*CP*GP*AP*A)-3'

Structural Keywords:

RH DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Horton, N.C., Finzel, B.C.
The structure of an RNA/DNA hybrid: a substrate of the ribonuclease activity of HIV-1 reverse transcriptase. 
J.Mol.Biol., 264, pp. 521 - 533, 1996.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 43 2 2

Cell Constants:

a = 31.3   b = 31.3   c = 137.7 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the X-PLOR program. The R value is 0.145 for 2457 reflections in the resolution range 5.0 to 2.3 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  0.0 sigma(I)