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NDB ID: UR0001    PDB ID: 429D 


Title:

CRYSTAL STRUCTURE OF A LEADZYME; METAL BINDING AND IMPLICATIONS FOR CATALYSIS

Molecular Description:

5'-R(*CP*GP*GP*AP*CP*CP*GP*AP*GP*CP*CP*AP*G)-3'
5'-R(*GP*CP*UP*GP*GP*GP*AP*GP* UP*CP*C)-3'

Structural Keywords:

DOUBLE HELIX, FLIPPED-OUT BASES, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Wedekind, J.E., McKay, D.B.
Crystal structure of a lead-dependent ribozyme revealing metal binding sites relevant to catalysis. 
Nat.Struct.Biol., 6, pp. 261 - 268, 1999.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 61 2 2

Cell Constants:

a = 60.4   b = 60.4   c = 133.1 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.255 for 4169 reflections in the resolution range 25.0 to 2.7 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)