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NDB ID: UR0081    PDB ID: 2GDI 


Title:

CRYSTAL STRUCTURE OF THIAMINE PYROPHOSPHATE-SPECIFIC RIBOSWITCH IN COMPLEX WITH THIAMINE PYROPHOSPHATE

Molecular Description:

TPP riboswitch

Deposited:

2006-03-16

Released:

2006-07-04

Structural Keywords:

, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Serganov, A., Polonskaia, A., Phan, A.T., Breaker, R.R., Patel, D.J.
Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch. 
Nature, 441, pp. 1167 - 1171, 2006.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 148.819   b = 29.558   c = 95.17 (Ångstroms)

α = 90.0   β = 94.55   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.21 for 25258 reflections in the resolution range 20.0 to 2.05 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)