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NDB ID: UR0122    PDB ID: 2QUW 


Title:

HAMMERHEAD RIBOZYME G12A MUTANT AFTER CLEAVAGE

Molecular Description:

5'-R(*(GTP)P*GP*GP*AP*GP*CP*CP*CP*UP*GP*UP*(CCC))-3'

Structural Keywords:

SINGLE STRAND, LOOPS, HAIRPIN LOOP, FLIPPED-OUT BASES, BULGES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Chi, Y.I., Martick, M., Lares, M., Kim, R., Scott, W.G., Kim, S.H.
Capturing hammerhead ribozyme structures in action by modulating general base catalysis. 
Plos Biol., 6, pp. e234 - e234, 2008.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1

Cell Constants:

a = 28.03   b = 53.14   c = 72.05 (Ångstroms)

α = 74.24   β = 81.37   γ = 75.65 (degrees)

Refinement:

The structure was refined using the REFMAC 5.2 program. The R value is 0.205 for 17539 reflections in the resolution range 19.46 to 2.2 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)