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NDB ID: URX075    PDB ID: 397D 


Title:

A 1.3 A RESOLUTION CRYSTAL STRUCTURE OF THE HIV-1 TRANS-ACTIVATION RESPONSE REGION RNA STEM REVEALS A METAL ION-DEPENDENT BULGE CONFORMATION

Molecular Description:

5'-R(*GP*GP*CP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP*CP*G)-3'

Structural Keywords:

DOUBLE HELIX, BULGE, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Ippolito, J.A., Steitz, T.A.
A 1.3-A resolution crystal structure of the HIV-1 trans-activation response region RNA stem reveals a metal ion-dependent bulge conformation. 
Proc.Natl.Acad.Sci.USA, 95, pp. 9819 - 9824, 1998.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1

Cell Constants:

a = 27.1   b = 27.1   c = 31.6 (Ångstroms)

α = 69.2   β = 77.5   γ = 63.0 (degrees)

Refinement:

The structure was refined using the SHELXL-97 program. The R value is 0.126 for 0 reflections in the resolution range 20.0 to 1.3 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)